Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.2
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg
†
Top Medical Research Studies
8
We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Read More
8
Vitamin E intake and heart health
We investigated how dietary vitamin E intake relates to cardiovascular disease and mortality using data from over 39,000 participants in the NHANES study from 2003 to 2018.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Read More
8
We examined various studies comparing tocotrienol and tocopherol, types of vitamin E, in managing atherosclerotic cardiovascular disease. After reviewing 516 articles, we found that tocotrienol significantly reduced cholesterol and inflammatory markers, showing promising benefits for heart health. In contrast, tocopherol presented mixed results, sometimes increasing mortality risk. This suggests that tocotrienol may be a safer and more effective choice for improving cardiovascular health.
Read More
Most Useful Reviews
9
Essential remedy
A quality remedy vital for the health of our cardiovascular system! Convenient capsules with no side effects!
Read More
7.5
Heart function improvement
This product enhances the functioning of the heart and blood vessels while lowering cholesterol, which is crucial for women over 50. As we age, the risk of developing cardiovascular disease increases.
Read More
6
Good health support
LAL benefits: Reducing blood sugar levels, improving nerve function, and protecting against cardiovascular disease. It helps me maintain good health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.2
- All Researches
9
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
8
Antioxidants reduce CVD mortality risk
We investigated the connection between dietary antioxidants, including vitamin E, and mortality risks in patients with cardiovascular disease (CVD). In our research with 1,395 participants, we found that higher levels of antioxidants were linked to decreased all-cause and cardiovascular-cause deaths.
Specifically, vitamins like C and E showed beneficial effects. This suggests that boosting our antioxidant intake could be a helpful strategy for improving health outcomes in those with CVD.
Specifically, vitamins like C and E showed beneficial effects. This suggests that boosting our antioxidant intake could be a helpful strategy for improving health outcomes in those with CVD.
Read More
8
We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Essential remedy
A quality remedy vital for the health of our cardiovascular system! Convenient capsules with no side effects!
Read More
7.5
Heart function improvement
This product enhances the functioning of the heart and blood vessels while lowering cholesterol, which is crucial for women over 50. As we age, the risk of developing cardiovascular disease increases.
Read More
6
Good health support
LAL benefits: Reducing blood sugar levels, improving nerve function, and protecting against cardiovascular disease. It helps me maintain good health.
Read More
Frequently Asked Questions
7.5
Heart function improvement
This product enhances the functioning of the heart and blood vessels while lowering cholesterol, which is crucial for women over 50. As we age, the risk of developing cardiovascular disease increases.
6
Good health support
LAL benefits: Reducing blood sugar levels, improving nerve function, and protecting against cardiovascular disease. It helps me maintain good health.
9
Essential remedy
A quality remedy vital for the health of our cardiovascular system! Convenient capsules with no side effects!
8
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
8
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
References
- Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13111400
- Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. doi:10.3389/fimmu.2024.1436747
- Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16172818
- Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. doi:10.6133/apjcn.202412_33(4).0005
- Hu X, Zhao Z, An Q, Li Y, Wang B. Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease. BMC Public Health. 2025;25:1327. doi:10.1186/s12889-025-22481-1
- Yang R, Lv M, Yang X, Zhai S. A Mendelian randomized study of circulating antioxidants in the diet and risk of cardiovascular disease. Sci Rep. 2025;15:10341. doi:10.1038/s41598-025-94369-4
- Czlapka-Matyasik M, Wadolowska L, Gut P, Gramza-Michałowska A. Changes in Oxidative Stress, Inflammatory Markers, and Lipid Profile After a 6-Week High-Antioxidant-Capacity Dietary Intervention in CVD Patients. Nutrients. 2025;17. doi:10.3390/nu17050806
- Ishihara N, Tanaka M, Namba K, Kawano S, Nishimura S, et al. Long-term exposure to urban particulate matter exacerbates mortality after ischemic stroke in mice. J Toxicol Sci. 2025;50:147. doi:10.2131/jts.50.147
- Zhao S, Cao Y, Liu H, Liu A. Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study. Nutr J. 2025;24:14. doi:10.1186/s12937-024-01062-9
- Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. doi:10.1016/j.ijcrp.2024.200340
- Ren W, Li Y, Lu C, Liu S, Shao Y, et al. Comprehensive assessment on the association of dietary vitamins with all-cause and cardiovascular mortality among individuals with prediabetes: evidence from NHANES 1999-2018. Food Funct. 2024;15:10037. doi:10.1039/d4fo02893g
- Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. doi:10.1038/s41598-024-68413-8
- Wang Y, Han L, Ling S, Sha Y, Sun H. Dietary intake of potassium, vitamin E, and vitamin C emerges as the most significant predictors of cardiovascular disease risk in adults. Medicine (Baltimore). 2024;103:e39180. doi:10.1097/MD.0000000000039180
- Rafique S, Khan DA, Farhat K, Khan MA, Noor M, et al. Comparative efficacy of tocotrienol and tocopherol (vitamin E) on atherosclerotic cardiovascular diseases in humans. J Pak Med Assoc. 2024;74:1124. doi:10.47391/JPMA.9227
- Sun Y, Zhang H, Qi G, Tian W. Nutrient deficiency patterns and all-cause and cardiovascular mortality in older adults with hypertension: a latent class analysis. BMC Public Health. 2024;24:1551. doi:10.1186/s12889-024-19003-w
- Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. doi:10.2147/CIA.S461821
- Yakoubi S. Synergistic integration of deep learning with protein docking in cardiovascular disease treatment strategies. IUBMB Life. 2024;76:666. doi:10.1002/iub.2819
- Liu C, Liang D. Association between Dietary Vitamin E Intake and the Risk of Hypertension in US Adults. Curr Vasc Pharmacol. 2024;22:391. doi:10.2174/0115701611297956240425115501
